Anti-GAA antibody (432-482 aa) (STJ193681)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human LYAG at the amino acid range 432-482
General Information
| Short Description | Rabbit polyclonal anti-Lysosomal alpha-glucosidase (432-482 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GAA |
| Gene ID | 2548 |
| Uniprot ID | LYAG_HUMAN |
| Immunogen | Synthesized peptide derived from the human LYAG at the amino acid range 432-482 |
| Immunogen Region | 432-482 aa |
| Specificity | This antibody detects endogenous levels of LYAG at Human/Mouse/Rat |
Additional Info
| Function | Essential for the degradation of glycogen in lysosomes. Has highest activity on alpha-1,4-linked glycosidic linkages, but can also hydrolyze alpha-1,6-linked glucans. |
| Protein Name | Lysosomal Alpha-GlucosidaseAcid MaltaseAglucosidase Alfa Cleaved Into - 76 Kda Lysosomal Alpha-Glucosidase - 70 Kda Lysosomal Alpha-Glucosidase |
| Database Links | Reactome: R-HSA-5357609Reactome: R-HSA-6798695Reactome: R-HSA-70221 |
| Cellular Localisation | LysosomeLysosome Membrane |
| Alternative Antibody Names | Anti-Lysosomal Alpha-Glucosidase antibodyAnti-Acid Maltase antibodyAnti-Aglucosidase Alfa Cleaved Into - 76 Kda Lysosomal Alpha-Glucosidase - 70 Kda Lysosomal Alpha-Glucosidase antibodyAnti-GAA antibody |
Information sourced from Uniprot.org