Anti-G6PD antibody (415-515) (STJ115918)

Name: Anti-G6PD antibody (415-515) (STJ115918)
SKU: STJ115918
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ115918

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Short Description	Rabbit polyclonal G6PD (415-515) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/IF/ICC/ELISA
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:1000 IF/ICC:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	G6PD
Gene ID	2539
Uniprot ID	G6PD_HUMAN
Immunogen Region	415-515
Immunogen Sequence	PEESELDLTYGNRYKNVKLP DAYERLILDVFCGSQMHFVR SDELREAWRIFTPLLHQIEL EKPKPIPYIYGSRGPTEADE LMKRVGFQYEGTYKWVNPHK L
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 415-515 of human G6PD (NP_001035810.1).

Tissue Specificity	Isoform Long is found in lymphoblasts, granulocytes and sperm.
Post Translational Modifications	Acetylated by ELP3 at Lys-403.acetylation inhibits its homodimerization and enzyme activity. Deacetylated by SIRT2 at Lys-403.deacetylation stimulates its enzyme activity.
Function	Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis.
Protein Name	Glucose-6-Phosphate 1-Dehydrogenase G6pd
Database Links	Reactome: R-HSA-5628897 Reactome: R-HSA-71336 Reactome: R-HSA-9818028
Cellular Localisation	Cytoplasm Cytosol Membrane Peripheral Membrane Protein
Alternative Antibody Names	Anti-Glucose-6-Phosphate 1-Dehydrogenase antibody Anti-G6pd antibody Anti-G6PD antibody

Information sourced from Uniprot.org