| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-G2/M phase-specific E3 ubiquitin-protein ligase (196-246) is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:1000-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | G2E3 |
| Gene ID: | 55632 |
| Uniprot ID: | G2E3_HUMAN |
| Immunogen Region: | 196-246 |
| Specificity: | This antibody detects endogenous levels of human G2E3 |
| Immunogen: | Synthesized peptide derived from human G2E3 AA range: 196-246 |
| Function | E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Essential in early embryonic development to prevent apoptotic death. |
| Protein Name | G2/M Phase-Specific E3 Ubiquitin-Protein LigaseG2/M Phase-Specific Hect-Type E3 Ubiquitin Transferase |
| Cellular Localisation | NucleusNucleolusCytoplasmShuttles Between The Nucleus And The CytoplasmIn The NucleusDelocalizes From The Nucleolus To The Nucleoplasm In Response To Dna Damage |
| Alternative Antibody Names | Anti-G2/M Phase-Specific E3 Ubiquitin-Protein Ligase antibodyAnti-G2/M Phase-Specific Hect-Type E3 Ubiquitin Transferase antibodyAnti-G2E3 antibodyAnti-KIAA1333 antibody |
Information sourced from Uniprot.org