Anti-G-CSF Receptor antibody [R08-6K3] (STJA0036526)

SKU:
STJA0036526
£133.50 - £281.50
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Short Description :Rabbit monoclonal anti-G-CSF Receptor for use in WB and FC in Human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/FC
Host:Rabbit
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :R08-6K3
Isotype:IgG
Conjugation:Unconjugated
Purification:Affinity Chromatography
Dilution Range:WB 1:500-1:1000
FC 1:50-1:100
Formulation:Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Instruction:Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol:CSF3R
Gene ID:1441
Uniprot ID:CSF3R_HUMAN
Immunogen:A synthesized peptide derived from human GCSF Receptor (CD114)
Tissue Specificity One or several isoforms have been found in myelogenous leukemia cell line KG-1, leukemia U-937 cell line, in bone marrow cells, placenta, and peripheral blood granulocytes. Isoform GCSFR-2 is found only in leukemia U-937 cells. Isoform GCSFR-3 is highly expressed in placenta.
Post Translational Modifications N-glycosylated.
Function Receptor for granulocyte colony-stimulating factor (CSF3), essential for granulocytic maturation. Plays a crucial role in the proliferation, differentiation and survival of cells along the neutrophilic lineage. In addition it may function in some adhesion or recognition events at the cell surface.
Protein Name Granulocyte Colony-Stimulating Factor Receptor
G-Csf Receptor
G-Csf-R
Cd Antigen Cd114
Database Links Reactome: R-HSA-449836
Reactome: R-HSA-9616222
Reactome: R-HSA-9674555
Reactome: R-HSA-9705462
Cellular Localisation Isoform 2: Secreted
Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Granulocyte Colony-Stimulating Factor Receptor antibody
Anti-G-Csf Receptor antibody
Anti-G-Csf-R antibody
Anti-Cd Antigen Cd114 antibody
Anti-CSF3R antibody
Anti-GCSFR antibody

Information sourced from Uniprot.org