Anti-FUT2 antibody (29-150) (STJ28288)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal FUT2 (29-150) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | FUT2 |
| Gene ID | 2524 |
| Uniprot ID | FUT2_HUMAN |
| Immunogen Region | 29-150 |
| Immunogen Sequence | QQRLAKIQAMWELPVQIPVL ASTSKALGPSQLRGMWTINA IGRLGNQMGEYATLYALAKM NGRPAFIPAQMHSTLAPIFR ITLPVLHSATASRIPWQNYH LNDWMEEEYRHIPGEYVRFT GY |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 29-150 of human FUT2 (NP_001091107.1). |
Additional Info
| Tissue Specificity | Small intestine, colon and lung. |
| Function | Catalyzes the transfer of L-fucose, from a guanosine diphosphate-beta-L-fucose, to the terminal galactose on both O- and N-linked glycans chains of cell surface glycoproteins and glycolipids and the resulting epitope regulates several processes such as cell-cell interaction including host-microbe interaction, cell surface expression and cell proliferation. Preferentially fucosylates gangliosides GA1 and GM1 in the antrum, cecum and colon and in the female reproductive organs. Fucosylated host glycoproteins or glycolipids mediate interaction with intestinal microbiota influencing its composition. Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen which is an essential substrate for the final step in the soluble ABO blood group antigen synthesis pathway. |
| Protein Name | Galactoside Alpha-(1 -2-Fucosyltransferase 2Alpha(1 -2ft 2Fucosyltransferase 2Gdp-L-Fucose -Beta-D-Galactoside 2-Alpha-L-Fucosyltransferase 2Se2Secretor Blood Group Alpha-2-FucosyltransferaseSecretor FactorSeType 1 Galactoside Alpha-(1 -2-Fucosyltransferase Fut2Type 2 Galactoside Alpha-(1 -2-Fucosyltransferase Fut2 |
| Database Links | Reactome: R-HSA-9033807Reactome: R-HSA-9037629Reactome: R-HSA-9840309 |
| Cellular Localisation | Golgi ApparatusGolgi Stack MembraneSingle-Pass Type Ii Membrane ProteinMembrane-Bound Form In Trans Cisternae Of Golgi |
| Alternative Antibody Names | Anti-Galactoside Alpha-(1 -2-Fucosyltransferase 2 antibodyAnti-Alpha(1 -2ft 2 antibodyAnti-Fucosyltransferase 2 antibodyAnti-Gdp-L-Fucose -Beta-D-Galactoside 2-Alpha-L-Fucosyltransferase 2 antibodyAnti-Se2 antibodyAnti-Secretor Blood Group Alpha-2-Fucosyltransferase antibodyAnti-Secretor Factor antibodyAnti-Se antibodyAnti-Type 1 Galactoside Alpha-(1 -2-Fucosyltransferase Fut2 antibodyAnti-Type 2 Galactoside Alpha-(1 -2-Fucosyltransferase Fut2 antibodyAnti-FUT2 antibodyAnti-SEC2 antibody |
Information sourced from Uniprot.org