Anti-FUNDC2 antibody (STJA0004736)

SKU:
STJA0004736
£140.50 - £415.50
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Host: Rabbit
Applications: IHC/ELISA
Reactivity: Human
Note: FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Fun14 Domain-Containing Protein 2 is suitable for use in Immunohistochemistry and ELISA research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification: Antigen affinity purification
Concentration: 1.02 mg/mL
Dilution Range: IHC 1:50-1:300
Storage Instruction: Store at-20°C for long term, and avoid freeze-thaw cycles.
Gene Symbol: FUNDC2
Gene ID: 65991
Uniprot ID: FUND2_HUMAN
Immunogen: Fusion protein of human FUNDC2
Tissue Specificity Highly expressed in platelets (at protein level).
Function Binds directly and specifically 1,2-Diacyl-sn-glycero-3-phospho-(1'-myo-inositol-3',4',5'-bisphosphate) (PIP3) leading to the recruitment of PIP3 to mitochondria and may play a role in the regulation of the platelet activation via AKT/GSK3B/cGMP signaling pathways. May act as transcription factor that regulates SREBP1 (isoform SREBP-1C) expression in order to modulate triglyceride (TG) homeostasis in hepatocytes.
Protein Name Fun14 Domain-Containing Protein 2
Cervical Cancer Proto-Oncogene 3 Protein
Hcc-3
Hepatitis C Virus Core-Binding Protein 6
Cellular Localisation Mitochondrion Outer Membrane
Multi-Pass Membrane Protein
Nucleus
Alternative Antibody Names Anti-Fun14 Domain-Containing Protein 2 antibody
Anti-Cervical Cancer Proto-Oncogene 3 Protein antibody
Anti-Hcc-3 antibody
Anti-Hepatitis C Virus Core-Binding Protein 6 antibody
Anti-FUNDC2 antibody
Anti-HCBP6 antibody
Anti-DC44 antibody
Anti-HCC3 antibody
Anti-PD03104 antibody

Information sourced from Uniprot.org

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