| Host: | Rabbit |
| Applications: | WB/IHC-P/IF/ICC/IP/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200IF/ICC:1:50-1:100IP:0.5 Mu g-4 Mu g antibody for 200 Mu g-400 Mu g extracts of whole cellsELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specif |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FUBP1 |
| Gene ID: | 8880 |
| Uniprot ID: | FUBP1_HUMAN |
| Immunogen Region: | 302-644 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 302-644 of human FUBP1 (NP_003893.2). |
| Immunogen Sequence: | QNDAGVRIQFKPDDGTTPER IAQITGPPDRCQHAAEIITD LLRSVQAGNPGGPGPGGRGR GRGQGNWNMGPPGGLQEFNF IVPTGKTGLIIGKGGETIKS ISQQSGARIELQRNPPPNAD PNMKLFTIRGTPQQIDYARQ LIEEKIGGPVNPLGPPVPHG PHGVPGPHGPPGPPGPGTPM GPYNPAPYNPGPPGPAPHGP PAPYAPQGWGNAYPHWQQQA PPDPAKAGTDPNSAAWAAY |
| Post Translational Modifications | Ubiquitinated. This targets the protein for proteasome-mediated degradation. |
| Function | Regulates MYC expression by binding to a single-stranded far-upstream element (FUSE) upstream of the MYC promoter. May act both as activator and repressor of transcription. |
| Protein Name | Far Upstream Element-Binding Protein 1FbpFuse-Binding Protein 1Dna Helicase VHdh V |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Far Upstream Element-Binding Protein 1 antibodyAnti-Fbp antibodyAnti-Fuse-Binding Protein 1 antibodyAnti-Dna Helicase V antibodyAnti-Hdh V antibodyAnti-FUBP1 antibody |
Information sourced from Uniprot.org