| Host: |
Rabbit |
| Applications: |
WB/IF/ICC/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Monoclonal |
| Clone ID: |
S9MR |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:1000-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
FTH1 |
| Gene ID: |
2495 |
| Uniprot ID: |
FRIH_HUMAN |
| Immunogen Region: |
1-100 |
| Specificity: |
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Ferritin Heavy Chain (P02794). |
| Immunogen Sequence: |
MTTASTSQVRQNYHQDSEAA INRQINLELYASYVYLSMSY YFDRDDVALKNFAKYFLHQS HEEREHAEKLMKLQNQRGGR IFLQDIKKPDCDDWESGLNA |
| Tissue Specificity | Expressed in the liver. |
| Function | Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney. Delivery to lysosomes is mediated by the cargo receptor NCOA4 for autophagic degradation and release of iron. |
| Protein Name | Ferritin Heavy ChainFerritin H SubunitCell Proliferation-Inducing Gene 15 Protein Cleaved Into - Ferritin Heavy Chain - N-Terminally Processed |
| Database Links | Reactome: R-HSA-3000480Reactome: R-HSA-432722Reactome: R-HSA-6798695Reactome: R-HSA-917937 |
| Cellular Localisation | CytoplasmLysosomeCytoplasmic VesicleAutophagosome |
| Alternative Antibody Names | Anti-Ferritin Heavy Chain antibodyAnti-Ferritin H Subunit antibodyAnti-Cell Proliferation-Inducing Gene 15 Protein Cleaved Into - Ferritin Heavy Chain - N-Terminally Processed antibodyAnti-FTH1 antibodyAnti-FTH antibodyAnti-FTHL6 antibodyAnti-OK antibodyAnti-SW-cl.84 antibodyAnti-PIG15 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
