| Short Description : | Rabbit polyclonal FTCD (412-541) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FTCD |
| Gene ID: | 10841 |
| Uniprot ID: | FTCD_HUMAN |
| Immunogen Region: | 412-541 |
| Immunogen Sequence: | DAEAFTAYLEAMRLPKNTPE EKDRRTAALQEGLRRAVSVP LTLAETVASLWPALQELARC GNLACRSDLQVAAKALEMGV FGAYFNVLINLRDITDEAFK DQIHHRVSSLLQEAKTQAAL VLDCLETRQE |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 412-541 of human FTCD (NP_006648.1). |
| Function | Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool. Binds and promotes bundling of vimentin filaments originating from the Golgi. |
| Protein Name | Formimidoyltransferase-CyclodeaminaseFormiminotransferase-CyclodeaminaseFtcdLchc1 Includes - Glutamate FormimidoyltransferaseGlutamate FormiminotransferaseGlutamate Formyltransferase - Formimidoyltetrahydrofolate CyclodeaminaseFormiminotetrahydrofolate Cyclodeaminase |
| Database Links | Reactome: R-HSA-70921 |
| Cellular Localisation | CytoplasmCytosolGolgi ApparatusCytoskeletonMicrotubule Organizing CenterCentrosomeCentrioleMore Abundantly Located Around The Mother Centriole |
| Alternative Antibody Names | Anti-Formimidoyltransferase-Cyclodeaminase antibodyAnti-Formiminotransferase-Cyclodeaminase antibodyAnti-Ftcd antibodyAnti-Lchc1 Includes - Glutamate Formimidoyltransferase antibodyAnti-Glutamate Formiminotransferase antibodyAnti-Glutamate Formyltransferase - Formimidoyltetrahydrofolate Cyclodeaminase antibodyAnti-Formiminotetrahydrofolate Cyclodeaminase antibodyAnti-FTCD antibody |
Information sourced from Uniprot.org
