| Host: | Mouse |
| Applications: | ELISA/FC/IF/Neut |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-Follicle-Stimulating Hormone Receptor is suitable for use in ELISA, Flow Cytometry, Immunofluorescence and Universal research applications. |
| Clonality : | Monoclonal |
| Clone ID : | 9H11 |
| Conjugation: | Unconjugated |
| Isotype: | IgG2ak |
| Formulation: | 0.01M PBS, pH 7.4, 0.09% Sodium azide. |
| Purification: | Protein A/G purified from cell culture supernatant. |
| Concentration: | 1 mg/ml |
| Storage Instruction: | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
| Gene Symbol: | FSHR |
| Gene ID: | 2492 |
| Uniprot ID: | FSHR_HUMAN |
| Post Translational Modifications | Sulfated. N-glycosylated.indirectly required for FSH-binding, possibly via a conformational change that allows high affinity binding of hormone. |
| Function | G protein-coupled receptor for follitropin, the follicle-stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. |
| Protein Name | Follicle-Stimulating Hormone ReceptorFsh-RFollitropin Receptor |
| Database Links | Reactome: R-HSA-375281Reactome: R-HSA-418555 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Follicle-Stimulating Hormone Receptor antibodyAnti-Fsh-R antibodyAnti-Follitropin Receptor antibodyAnti-FSHR antibodyAnti-LGR1 antibody |
Information sourced from Uniprot.org