Post Translational Modifications | Sulfated. N-glycosylated.indirectly required for FSH-binding, possibly via a conformational change that allows high affinity binding of hormone. |
Function | G protein-coupled receptor for follitropin, the follicle-stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. |
Protein Name | Follicle-Stimulating Hormone ReceptorFsh-RFollitropin Receptor |
Database Links | Reactome: R-HSA-375281Reactome: R-HSA-418555 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
Alternative Antibody Names | Anti-Follicle-Stimulating Hormone Receptor antibodyAnti-Fsh-R antibodyAnti-Follitropin Receptor antibodyAnti-FSHR antibodyAnti-LGR1 antibody |
Information sourced from Uniprot.org