| Short Description : | Rabbit polyclonal anti-Secreted frizzled-related protein 3 (150-230 aa) for use in WB, IHC, IF and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC/IF/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:40000IF 1:50-200 |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FRZB |
| Gene ID: | 2487 |
| Uniprot ID: | SFRP3_HUMAN |
| Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 150-230 |
| Immunogen Region: | 150-230 aa |
| Specificity: | SFRP3 Polyclonal Antibody detects endogenous levels of protein. |
| Function | Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP3/FRZB appears to be involved in limb skeletogenesis. Antagonist of Wnt8 signaling. Regulates chondrocyte maturation and long bone development. |
| Protein Name | Secreted Frizzled-Related Protein 3Sfrp-3FrezzledFritzFrizzled-Related Protein 1Frzb-1 |
| Database Links | |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Secreted Frizzled-Related Protein 3 antibodyAnti-Sfrp-3 antibodyAnti-Frezzled antibodyAnti-Fritz antibodyAnti-Frizzled-Related Protein 1 antibodyAnti-Frzb-1 antibodyAnti-FRZB antibodyAnti-FIZ antibodyAnti-FRE antibodyAnti-FRP antibodyAnti-FRZB1 antibodyAnti-SFRP3 antibody |
Information sourced from Uniprot.org
