Host: |
Rabbit |
Applications: |
WB/IHC/IF/ELISA |
Reactivity: |
Human/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Secreted frizzled-related protein 3 (150-230 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-1:2000IHC 1:100-1:300ELISA 1:40000IF 1:50-200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
FRZB |
Gene ID: |
2487 |
Uniprot ID: |
SFRP3_HUMAN |
Immunogen Region: |
150-230 aa |
Specificity: |
SFRP3 Polyclonal Antibody detects endogenous levels of protein. |
Immunogen: |
Synthesized peptide derived from the human protein at the amino acid range 150-230 |
Function | Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP3/FRZB appears to be involved in limb skeletogenesis. Antagonist of Wnt8 signaling. Regulates chondrocyte maturation and long bone development. |
Protein Name | Secreted Frizzled-Related Protein 3Sfrp-3FrezzledFritzFrizzled-Related Protein 1Frzb-1 |
Cellular Localisation | Secreted |
Alternative Antibody Names | Anti-Secreted Frizzled-Related Protein 3 antibodyAnti-Sfrp-3 antibodyAnti-Frezzled antibodyAnti-Fritz antibodyAnti-Frizzled-Related Protein 1 antibodyAnti-Frzb-1 antibodyAnti-FRZB antibodyAnti-FIZ antibodyAnti-FRE antibodyAnti-FRP antibodyAnti-FRZB1 antibodyAnti-SFRP3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance