Host: | Rabbit |
Applications: | WB/IHC/IF/ELISA |
Reactivity: | Human/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-Secreted frizzled-related protein 3 (150-230 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-1:2000 IHC 1:100-1:300 ELISA 1:40000 IF 1:50-200 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | FRZB |
Gene ID: | 2487 |
Uniprot ID: | SFRP3_HUMAN |
Immunogen Region: | 150-230 aa |
Specificity: | SFRP3 Polyclonal Antibody detects endogenous levels of protein. |
Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 150-230 |
Function | Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP3/FRZB appears to be involved in limb skeletogenesis. Antagonist of Wnt8 signaling. Regulates chondrocyte maturation and long bone development. |
Protein Name | Secreted Frizzled-Related Protein 3 Sfrp-3 Frezzled Fritz Frizzled-Related Protein 1 Frzb-1 |
Cellular Localisation | Secreted |
Alternative Antibody Names | Anti-Secreted Frizzled-Related Protein 3 antibody Anti-Sfrp-3 antibody Anti-Frezzled antibody Anti-Fritz antibody Anti-Frizzled-Related Protein 1 antibody Anti-Frzb-1 antibody Anti-FRZB antibody Anti-FIZ antibody Anti-FRE antibody Anti-FRP antibody Anti-FRZB1 antibody Anti-SFRP3 antibody |
Information sourced from Uniprot.org