| Short Description : | Rabbit polyclonal anti-N-formyl peptide receptor 3 (304-353 aa) for use in IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | IF/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | IF 1:200-1:1000ELISA 1:40000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FPR3 |
| Gene ID: | 2359 |
| Uniprot ID: | FPR3_HUMAN |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human FPRL2 at the amino acid range 304-353 |
| Immunogen Region: | 304-353 aa |
| Specificity: | FPRL2 Polyclonal Antibody detects endogenous levels of FPRL2 protein. |
| Function | Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Acts as a receptor for humanin. |
| Protein Name | N-Formyl Peptide Receptor 3Fmlp-Related Receptor IiFmlp-R-IiFormyl Peptide Receptor-Like 2 |
| Database Links | Reactome: R-HSA-418594Reactome: R-HSA-444473 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-N-Formyl Peptide Receptor 3 antibodyAnti-Fmlp-Related Receptor Ii antibodyAnti-Fmlp-R-Ii antibodyAnti-Formyl Peptide Receptor-Like 2 antibodyAnti-FPR3 antibodyAnti-FPRH1 antibodyAnti-FPRL2 antibody |
Information sourced from Uniprot.org
