| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.09% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FOXP2 |
| Gene ID: | 93986 |
| Uniprot ID: | FOXP2_HUMAN |
| Immunogen Region: | 590-715 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 590-715 of human FOXP2 (NP_055306.1). |
| Immunogen Sequence: | GSPTLVKNIPTSLGYGAALN ASLQAALAESSLPLLSNPGL INNASSGLLQAVHEDLNGSL DHIDSNGNSSPGCSPQPHIH SIHVKEEPVIAEDEDCPMSL VTTANHSPELEDDREIEEEP LSEDLE |
| Tissue Specificity | Isoform 1 and isoform 6 are expressed in adult and fetal brain, caudate nucleus and lung. |
| Function | Transcriptional repressor that may play a role in the specification and differentiation of lung epithelium. May also play a role in developing neural, gastrointestinal and cardiovascular tissues. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Plays a role in synapse formation by regulating SRPX2 levels. Involved in neural mechanisms mediating the development of speech and language. |
| Protein Name | Forkhead Box Protein P2Cag Repeat Protein 44Trinucleotide Repeat-Containing Gene 10 Protein |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Forkhead Box Protein P2 antibodyAnti-Cag Repeat Protein 44 antibodyAnti-Trinucleotide Repeat-Containing Gene 10 Protein antibodyAnti-FOXP2 antibodyAnti-CAGH44 antibodyAnti-TNRC10 antibody |
Information sourced from Uniprot.org