| Short Description : | Mouse monoclonal anti-Forkhead box protein D3 for use in WB, IHC, IF and ELISA in Human, Mouse and Monkey samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC/IF/ELISA |
| Host: | Mouse |
| Reactivity: | Human/Mouse/Monkey |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | 5G9 |
| Isotype: | IgG1 |
| Conjugation: | Unconjugated |
| Purification: | Affinity purification |
| Dilution Range: | WB 1:500-1:2000IHC 1:200-1:1000ELISA 1:10000IF 1:50-200 |
| Formulation: | Liquid in PBS containing 0.03% Sodium Azide, 0.5% BSA, 50% Glycerol. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FOXD3 |
| Gene ID: | 27022 |
| Uniprot ID: | FOXD3_HUMAN |
| Immunogen: | Purified recombinant fragment of human FoxD3 expressed in E. Coli. |
| Specificity: | FoxD3 Monoclonal Antibody detects endogenous levels of FoxD3 protein. |
| Function | Binds to the consensus sequence 5'-AATTAGTTTGTTT-3' and acts as a transcriptional repressor. Also acts as a transcriptional activator. Negatively regulates transcription of transcriptional repressor RHIT/ZNF205. Promotes development of neural crest cells from neural tube progenitors. Restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation. Required for maintenance of pluripotent cells in the pre-implantation and peri-implantation stages of embryogenesis. |
| Protein Name | Forkhead Box Protein D3Hnf3/Fh Transcription Factor Genesis |
| Database Links | Reactome: R-HSA-2892247Reactome: R-HSA-9856649 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Forkhead Box Protein D3 antibodyAnti-Hnf3/Fh Transcription Factor Genesis antibodyAnti-FOXD3 antibodyAnti-HFH2 antibody |
Information sourced from Uniprot.org
