| Host: | Goat |
| Applications: | Pep-ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-Formyl Peptide Receptor-like 2 (C-Term) is suitable for use in ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:1000.WB: Preliminary experiments gave an approx 55kDa band in Human Lymph Node lysates after 0.3µg/ml antibody staining. Please note that currently we cannot find an explanation in the literatur |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | FPR3 |
| Gene ID: | 2359 |
| Uniprot ID: | FPR3_HUMAN |
| Immunogen Region: | C-Term |
| Accession Number: | NP_002021.3 |
| Immunogen Sequence: | DSAQTSNTDTTS |
| Function | Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Acts as a receptor for humanin. |
| Protein Name | N-Formyl Peptide Receptor 3Fmlp-Related Receptor IiFmlp-R-IiFormyl Peptide Receptor-Like 2 |
| Database Links | Reactome: R-HSA-418594Reactome: R-HSA-444473 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-N-Formyl Peptide Receptor 3 antibodyAnti-Fmlp-Related Receptor Ii antibodyAnti-Fmlp-R-Ii antibodyAnti-Formyl Peptide Receptor-Like 2 antibodyAnti-FPR3 antibodyAnti-FPRH1 antibodyAnti-FPRL2 antibody |
Information sourced from Uniprot.org