| Short Description : | Rabbit polyclonal anti-Folate receptor beta for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FOLR2 |
| Gene ID: | 2350 |
| Uniprot ID: | FOLR2_HUMAN |
| Immunogen: | Synthesized peptide derived from part of the human protein |
| Specificity: | FOLR2 Polyclonal Antibody detects endogenous levels of protein. |
| Post Translational Modifications | N-glycosylated. |
| Function | Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. |
| Protein Name | Folate Receptor BetaFr-BetaFolate Receptor 2Folate Receptor - Fetal/PlacentalPlacental Folate-Binding ProteinFbp |
| Database Links | Reactome: R-HSA-163125Reactome: R-HSA-196757 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-AnchorSecreted |
| Alternative Antibody Names | Anti-Folate Receptor Beta antibodyAnti-Fr-Beta antibodyAnti-Folate Receptor 2 antibodyAnti-Folate Receptor - Fetal/Placental antibodyAnti-Placental Folate-Binding Protein antibodyAnti-Fbp antibodyAnti-FOLR2 antibody |
Information sourced from Uniprot.org
