Anti-FOLH1/PSMA nanobody [SAA2305] (STJN000685)
SPECIFICATIONS
ClonalityMonoclonal
HostAlpaca
ConjugationUnconjugated
IsotypeVHH-His
General Information
| Short Description | Alpaca monoclonal nanobody anti-FOLH1/PSMA is suitable for use in ELISA research applications. |
| Applications | ELISA |
| Host | Alpaca |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SAA2305 |
| Isotype | VHH-His |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Purified by Nickel column. |
| Dilution Range | ELISA: 1:2000-1:20000 |
| Formulation | 0.01M PBS pH 7.4 |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | Please contact with the lab for this information. |
Target Information
| Gene Symbol | FOLH1 |
| Gene ID | 2346 |
| Uniprot ID | FOLH1_HUMAN |
Additional Info
| Post Translational Modifications | The first two amino acids at the N-terminus of isoform PSMA' appear to be cleaved by limited proteolysis. The N-terminus is blocked. |
| Function | Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate. Involved in prostate tumor progression. Also exhibits a dipeptidyl-peptidase IV type activity. In vitro, cleaves Gly-Pro-AMC. |
| Protein Name | Glutamate Carboxypeptidase 2Cell Growth-Inhibiting Gene 27 ProteinFolate Hydrolase 1Folylpoly-Gamma-Glutamate CarboxypeptidaseFgcpGlutamate Carboxypeptidase IiGcpiiMembrane Glutamate CarboxypeptidaseMgcpN-Acetylated-Alpha-Linked Acidic Dipeptidase INaaladase IProstate-Specific Membrane AntigenPsmPsmaPteroylpoly-Gamma-Glutamate Carboxypeptidase |
| Database Links | Reactome: R-HSA-8963693 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane ProteinIsoform Psma': Cytoplasm |
| Alternative Nanobody Names | Anti-Glutamate Carboxypeptidase 2 nanobodyAnti-Cell Growth-Inhibiting Gene 27 Protein nanobodyAnti-Folate Hydrolase 1 nanobodyAnti-Folylpoly-Gamma-Glutamate Carboxypeptidase nanobodyAnti-Fgcp nanobodyAnti-Glutamate Carboxypeptidase Ii nanobodyAnti-Gcpii nanobodyAnti-Membrane Glutamate Carboxypeptidase nanobodyAnti-Mgcp nanobodyAnti-N-Acetylated-Alpha-Linked Acidic Dipeptidase I nanobodyAnti-Naaladase I nanobodyAnti-Prostate-Specific Membrane Antigen nanobodyAnti-Psm nanobodyAnti-Psma nanobodyAnti-Pteroylpoly-Gamma-Glutamate Carboxypeptidase nanobodyAnti-FOLH1 nanobodyAnti-FOLH nanobodyAnti-NAALAD1 nanobodyAnti-PSM nanobodyAnti-PSMA nanobodyAnti-GIG27 nanobody |
Information sourced from Uniprot.org