Anti-FOLH1/PSMA nanobody [SAA2305] (STJN000685)

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STJN000685
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Short Description :Alpaca monoclonal nanobody anti-FOLH1/PSMA is suitable for use in ELISA research applications.
Applications:ELISA
Host:Alpaca
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :SAA2305
Isotype:VHH-His
Conjugation:Unconjugated
Concentration:Lot specific
Purification:Purified by Nickel column.
Dilution Range:ELISA: 1:2000-1:20000
Formulation:0.01M PBS pH 7.4
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin:Please contact with the lab for this information.
Gene Symbol:FOLH1
Gene ID:2346
Uniprot ID:FOLH1_HUMAN
Post Translational Modifications The first two amino acids at the N-terminus of isoform PSMA' appear to be cleaved by limited proteolysis. The N-terminus is blocked.
Function Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate. Involved in prostate tumor progression. Also exhibits a dipeptidyl-peptidase IV type activity. In vitro, cleaves Gly-Pro-AMC.
Protein Name Glutamate Carboxypeptidase 2
Cell Growth-Inhibiting Gene 27 Protein
Folate Hydrolase 1
Folylpoly-Gamma-Glutamate Carboxypeptidase
Fgcp
Glutamate Carboxypeptidase Ii
Gcpii
Membrane Glutamate Carboxypeptidase
Mgcp
N-Acetylated-Alpha-Linked Acidic Dipeptidase I
Naaladase I
Prostate-Specific Membrane Antigen
Psm
Psma
Pteroylpoly-Gamma-Glutamate Carboxypeptidase
Database Links Reactome: R-HSA-8963693
Cellular Localisation Cell Membrane
Single-Pass Type Ii Membrane Protein
Isoform Psma': Cytoplasm
Alternative Nanobody Names Anti-Glutamate Carboxypeptidase 2 nanobody
Anti-Cell Growth-Inhibiting Gene 27 Protein nanobody
Anti-Folate Hydrolase 1 nanobody
Anti-Folylpoly-Gamma-Glutamate Carboxypeptidase nanobody
Anti-Fgcp nanobody
Anti-Glutamate Carboxypeptidase Ii nanobody
Anti-Gcpii nanobody
Anti-Membrane Glutamate Carboxypeptidase nanobody
Anti-Mgcp nanobody
Anti-N-Acetylated-Alpha-Linked Acidic Dipeptidase I nanobody
Anti-Naaladase I nanobody
Anti-Prostate-Specific Membrane Antigen nanobody
Anti-Psm nanobody
Anti-Psma nanobody
Anti-Pteroylpoly-Gamma-Glutamate Carboxypeptidase nanobody
Anti-FOLH1 nanobody
Anti-FOLH nanobody
Anti-NAALAD1 nanobody
Anti-PSM nanobody
Anti-PSMA nanobody
Anti-GIG27 nanobody

Information sourced from Uniprot.org