| Post Translational Modifications | Phosphorylated. Phosphorylation is mediated by MUSK upon AGRIN stimulation and results in the activation of FNTA. |
| Function | Essential subunit of both the farnesyltransferase and the geranylgeranyltransferase complex. Contributes to the transfer of a farnesyl or geranylgeranyl moiety from farnesyl or geranylgeranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. May positively regulate neuromuscular junction development downstream of MUSK via its function in RAC1 prenylation and activation. |
| Protein Name | Protein Farnesyltransferase/Geranylgeranyltransferase Type-1 Subunit AlphaCaax Farnesyltransferase Subunit AlphaFtase-AlphaRas Proteins Prenyltransferase Subunit AlphaType I Protein Geranyl-Geranyltransferase Subunit AlphaGgtase-I-Alpha |
| Database Links | Reactome: R-HSA-111465Reactome: R-HSA-2514859Reactome: R-HSA-9648002Reactome: R-HSA-9679191 |
| Alternative Antibody Names | Anti-Protein Farnesyltransferase/Geranylgeranyltransferase Type-1 Subunit Alpha antibodyAnti-Caax Farnesyltransferase Subunit Alpha antibodyAnti-Ftase-Alpha antibodyAnti-Ras Proteins Prenyltransferase Subunit Alpha antibodyAnti-Type I Protein Geranyl-Geranyltransferase Subunit Alpha antibodyAnti-Ggtase-I-Alpha antibodyAnti-FNTA antibody |
Information sourced from Uniprot.org
