| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FN3KRP |
| Gene ID: | 79672 |
| Uniprot ID: | KT3K_HUMAN |
| Immunogen Region: | 1-309 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-309 of human FN3KRP (NP_078895.2). |
| Immunogen Sequence: | MEELLRRELGCSSVRATGHS GGGCISQGRSYDTDQGRVFV KVNPKAEARRMFEGEMASLT AILKTNTVKVPKPIKVLDAP GGGSVLVMEHMDMRHLSSHA AKLGAQLADLHLDNKKLGEM RLKEAGTVGRGGGQEERPFV ARFGFDVVTCCGYLPQVNDW QEDWVVFYARQRIQPQMDMV EKESGDREALQLWSALQLKI PDLFRDLEIIPALLHGDLWG GNVAEDSSGPVIFDPASFY |
| Tissue Specificity | Widely expressed.except in skeletal muscle where it is expressed at very low level. Expressed in erythrocytes. |
| Function | Ketosamine-3-kinase involved in protein deglycation by mediating phosphorylation of ribuloselysine and psicoselysine on glycated proteins, to generate ribuloselysine-3 phosphate and psicoselysine-3 phosphate, respectively. Ribuloselysine-3 phosphate and psicoselysine-3 phosphate adducts are unstable and decompose under physiological conditions. Not able to phosphorylate fructoselysine. |
| Protein Name | Ketosamine-3-KinaseFructosamine-3-Kinase-Related ProteinFn3k-RpFn3k-Related ProteinProtein-Psicosamine 3-Kinase Fn3krp |
| Database Links | Reactome: R-HSA-163841 |
| Alternative Antibody Names | Anti-Ketosamine-3-Kinase antibodyAnti-Fructosamine-3-Kinase-Related Protein antibodyAnti-Fn3k-Rp antibodyAnti-Fn3k-Related Protein antibodyAnti-Protein-Psicosamine 3-Kinase Fn3krp antibodyAnti-FN3KRP antibody |
Information sourced from Uniprot.org