| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Fructosamine-3-kinase (130-210 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FN3K |
| Gene ID: | 64122 |
| Uniprot ID: | FN3K_HUMAN |
| Immunogen Region: | 130-210 aa |
| Specificity: | FN3K Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 130-210 |
| Function | Fructosamine-3-kinase involved in protein deglycation by mediating phosphorylation of fructoselysine residues on glycated proteins, to generate fructoselysine-3 phosphate. Fructoselysine-3 phosphate adducts are unstable and decompose under physiological conditions. Involved in intracellular deglycation in erythrocytes. Involved in the response to oxidative stress by mediating deglycation of NFE2L2/NRF2, glycation impairing NFE2L2/NRF2 function. Also able to phosphorylate psicosamines and ribulosamines. |
| Protein Name | Fructosamine-3-KinaseProtein-Psicosamine 3-Kinase Fn3kProtein-Ribulosamine 3-Kinase Fn3k |
| Database Links | Reactome: R-HSA-163841 |
| Alternative Antibody Names | Anti-Fructosamine-3-Kinase antibodyAnti-Protein-Psicosamine 3-Kinase Fn3k antibodyAnti-Protein-Ribulosamine 3-Kinase Fn3k antibodyAnti-FN3K antibody |
Information sourced from Uniprot.org