| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Flavin-containing monooxygenase 5 is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FMO5 |
| Gene ID: | 2330 |
| Uniprot ID: | FMO5_HUMAN |
| Specificity: | This antibody detects endogenous levels of FMO5 at Human, Mouse, Rat |
| Immunogen: | Synthesized peptide derived from human FMO5 |
| Function | Acts as a Baeyer-Villiger monooxygenase on a broad range of substrates. Catalyzes the insertion of an oxygen atom into a carbon-carbon bond adjacent to a carbonyl, which converts ketones to esters. Active on diverse carbonyl compounds, whereas soft nucleophiles are mostly non- or poorly reactive. In contrast with other forms of FMO it is non- or poorly active on 'classical' substrates such as drugs, pesticides, and dietary components containing soft nucleophilic heteroatoms (Probable). Able to oxidize drug molecules bearing a carbonyl group on an aliphatic chain, such as nabumetone and pentoxifylline. Also, in the absence of substrates, shows slow but yet significant NADPH oxidase activity. Acts as a positive modulator of cholesterol biosynthesis as well as glucose homeostasis, promoting metabolic aging via pleiotropic effects. |
| Protein Name | Flavin-Containing Monooxygenase 5 Fmo 5 Baeyer-Villiger Monooxygenase 1 Hbvmo1 Dimethylaniline Monooxygenase N-Oxide-Forming 5 Dimethylaniline Oxidase 5 Nadph Oxidase |
| Cellular Localisation | Microsome Membrane Endoplasmic Reticulum Membrane |
| Alternative Antibody Names | Anti-Flavin-Containing Monooxygenase 5 antibody Anti-Fmo 5 antibody Anti-Baeyer-Villiger Monooxygenase 1 antibody Anti-Hbvmo1 antibody Anti-Dimethylaniline Monooxygenase N-Oxide-Forming 5 antibody Anti-Dimethylaniline Oxidase 5 antibody Anti-Nadph Oxidase antibody Anti-FMO5 antibody |
Information sourced from Uniprot.org