| Host: | Goat |
| Applications: | Pep-ELISA/WB/IHC |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-Flotillin 2/FLOT2 (C-Term) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Approx 48kDa band observed in Human Brain (Cerebellum) , Lung and Testis lysates (calculated MW of 47.1kDa according to NP_004466.2). Recommended concentration: 0.1-0.3µg/ml.IHC: |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | FLOT2 |
| Gene ID: | 2319 |
| Uniprot ID: | FLOT2_HUMAN |
| Immunogen Region: | C-Term |
| Accession Number: | NP_004466.2 |
| Immunogen Sequence: | SKIPLIKKATGVQV |
| Post Translational Modifications | ZDHHC5-catalyzed palmitoylation predominantly occurs at Cys-4. ZDHHC5-catalyzed palmitoylation may be required for the formation of higher-order complexes and for neurite outgrowth in cultured neural stem cells. |
| Function | May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. May be involved in epidermal cell adhesion and epidermal structure and function. |
| Protein Name | Flotillin-2Epidermal Surface AntigenEsaMembrane Component Chromosome 17 Surface Marker 1 |
| Database Links | Reactome: R-HSA-5213460Reactome: R-HSA-5675482Reactome: R-HSA-8849932Reactome: R-HSA-8980692Reactome: R-HSA-9013026Reactome: R-HSA-9013106Reactome: R-HSA-9696264Reactome: R-HSA-9696273 |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinMembraneCaveolaEndosomeLipid-AnchorMembrane-Associated Protein Of Caveolae |
| Alternative Antibody Names | Anti-Flotillin-2 antibodyAnti-Epidermal Surface Antigen antibodyAnti-Esa antibodyAnti-Membrane Component Chromosome 17 Surface Marker 1 antibodyAnti-FLOT2 antibodyAnti-ESA1 antibodyAnti-M17S1 antibody |
Information sourced from Uniprot.org
