| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit monoclonal antibody anti-FLAP (62-161) is suitable for use in Western Blot research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
S2MR |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ALOX5AP |
| Gene ID: |
241 |
| Uniprot ID: |
AL5AP_HUMAN |
| Immunogen Region: |
62-161 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 62-161 of human FLAP (P20292). |
| Immunogen Sequence: |
DAYPTFLAVLWSAGLLCSQV PAAFAGLMYLFVRQKYFVGY LGERTQSTPGYIFGKRIILF LFLMSVAGIFNYYLIFFFGS DFENYIKTISTTISPLLLIP |
| Function | Required for leukotriene biosynthesis by ALOX5 (5-lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes. |
| Protein Name | Arachidonate 5-Lipoxygenase-Activating ProteinFlapMk-886-Binding Protein |
| Database Links | Reactome: R-HSA-2142688Reactome: R-HSA-2142691Reactome: R-HSA-2142700 |
| Cellular Localisation | Nucleus MembraneMulti-Pass Membrane ProteinEndoplasmic Reticulum Membrane |
| Alternative Antibody Names | Anti-Arachidonate 5-Lipoxygenase-Activating Protein antibodyAnti-Flap antibodyAnti-Mk-886-Binding Protein antibodyAnti-ALOX5AP antibodyAnti-FLAP antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
