Anti-FLAP antibody (62-161) [S2MR] (STJ11103062)

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STJ11103062
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Monoclonal
Clone ID : S2MR
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:1000-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ALOX5AP
Gene ID: 241
Uniprot ID: AL5AP_HUMAN
Immunogen Region: 62-161
Specificity: A synthetic peptide corresponding to a sequence within amino acids 62-161 of human FLAP (P20292).
Immunogen Sequence: DAYPTFLAVLWSAGLLCSQV PAAFAGLMYLFVRQKYFVGY LGERTQSTPGYIFGKRIILF LFLMSVAGIFNYYLIFFFGS DFENYIKTISTTISPLLLIP
Function Required for leukotriene biosynthesis by ALOX5 (5-lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes.
Protein Name Arachidonate 5-Lipoxygenase-Activating Protein
Flap
Mk-886-Binding Protein
Database Links Reactome: R-HSA-2142688
Reactome: R-HSA-2142691
Reactome: R-HSA-2142700
Cellular Localisation Nucleus Membrane
Multi-Pass Membrane Protein
Endoplasmic Reticulum Membrane
Alternative Antibody Names Anti-Arachidonate 5-Lipoxygenase-Activating Protein antibody
Anti-Flap antibody
Anti-Mk-886-Binding Protein antibody
Anti-ALOX5AP antibody
Anti-FLAP antibody

Information sourced from Uniprot.org