| Host: |
Mouse |
| Applications: |
WB/IHC |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Mouse monoclonal antibody anti-FHOD1 (Full Length) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
M352 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG1 |
| Formulation: |
PBS + 1 mg/ml BSA, 0.05% NaN3 and 50% glycerol |
| Purification: |
Antigen Affinity Purified |
| Dilution Range: |
WB 1:250IHC 1:50ICCIP |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
FHOD1 |
| Gene ID: |
29109 |
| Uniprot ID: |
FHOD1_HUMAN |
| Immunogen Region: |
Full Length |
| Specificity: |
The antibody detects a 140 kDa* protein corresponding to the apparent molecular mass of FHOD1 on SDS-PAGE immunoblots of human K562 and Jurkat, and has weak reactivity to FHOD1 in mouse C2C12. |
| Immunogen: |
FHOD1 recombinant protein that included the full length human FHOD1 sequence. This sequence has 50% homology to human FHOD3, and low homology to other formin family members. |
| Tissue Specificity | Ubiquitous. Highly expressed in spleen. |
| Post Translational Modifications | Phosphorylated by ROCK1. |
| Function | Required for the assembly of F-actin structures, such as stress fibers. Depends on the Rho-ROCK cascade for its activity. Contributes to the coordination of microtubules with actin fibers and plays a role in cell elongation. Acts synergistically with ROCK1 to promote SRC-dependent non-apoptotic plasma membrane blebbing. |
| Protein Name | Fh1/Fh2 Domain-Containing Protein 1Formin Homolog Overexpressed In Spleen 1FhosFormin Homology 2 Domain-Containing Protein 1 |
| Cellular Localisation | CytoplasmCytoskeletonCell ProjectionBlebPredominantly Cytoplasmic |
| Alternative Antibody Names | Anti-Fh1/Fh2 Domain-Containing Protein 1 antibodyAnti-Formin Homolog Overexpressed In Spleen 1 antibodyAnti-Fhos antibodyAnti-Formin Homology 2 Domain-Containing Protein 1 antibodyAnti-FHOD1 antibodyAnti-FHOS antibodyAnti-FHOS1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
