• Western blot analysis of extracts of HepG2 cells, using FGL1 antibody (STJ11103965) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-FGL1 antibody (Full Length) [S3965RM] (STJ11103965)

SKU:
STJ11103965

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Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-Fibrinogen-Like Protein 1 (Full Length) is suitable for use in Western Blot research applications.
Clonality: Monoclonal
Clone ID: S3965RM
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: FGL1
Gene ID: 2267
Uniprot ID: FGL1_HUMAN
Immunogen Region: Full Length
Immunogen: Recombinant protein of human FGL-1 Full length (NP_004458.3).
Immunogen Sequence: MAKVFSFILVTTALTMGREI SALEDCAQEQMRLRAQVRLL ETRVKQQQVKIKQLLQENEV QFLDKGDENTVIDLGSKRQY ADCSEIFNDGYKLSGFYKIK PLQSPAEFSVYCDMSDGGGW TVIQRRSDGSENFNRGWKDY ENGFGNFVQKHGEYWLGNKN LHFLTTQEDYTLKIDLADFE KNSRYAQYKNFKVGDEKNFY ELNIGEYSGTAGDSLAGNFH PEVQWWASHQRMKFSTWDR
Tissue Specificity Under normal conditions, liver-specific.
Function Immune suppressive molecule that inhibits antigen-specific T-cell activation by acting as a major ligand of LAG3. Responsible for LAG3 T-cell inhibitory function. Binds LAG3 independently from MHC class II (MHC-II). Secreted by, and promotes growth of, hepatocytes.
Protein Name Fibrinogen-Like Protein 1
Hp-041
Hepassocin
Hps
Hepatocyte-Derived Fibrinogen-Related Protein 1
Hfrep-1
Liver Fibrinogen-Related Protein 1
Lfire-1
Cellular Localisation Secreted
Secreted In The Blood Plasma
Alternative Antibody Names Anti-Fibrinogen-Like Protein 1 antibody
Anti-Hp-041 antibody
Anti-Hepassocin antibody
Anti-Hps antibody
Anti-Hepatocyte-Derived Fibrinogen-Related Protein 1 antibody
Anti-Hfrep-1 antibody
Anti-Liver Fibrinogen-Related Protein 1 antibody
Anti-Lfire-1 antibody
Anti-FGL1 antibody
Anti-HFREP1 antibody

Information sourced from Uniprot.org

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