Anti-FGF13 antibody [N91/271R] (STJA0019323)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2a
General Information
| Short Description | Mouse monoclonal Fibroblast Growth Factor 13 antibody for use in IF and WB in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IF/WB |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS |
Product Properties
| Clonality | Monoclonal |
| Clone ID | N91/271R |
| Isotype | IgG2a |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Protein A/G purified from cell culture supernatant |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months |
Target Information
| Gene Symbol | FGF13 |
| Gene ID | 2258 |
| Uniprot ID | FGF13_HUMAN |
Additional Info
| Post Translational Modifications | May be phosphorylated. |
| Function | Microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules. Through its action on microtubules, may participate in the refinement of axons by negatively regulating axonal and leading processes branching. Plays a crucial role in neuron polarization and migration in the cerebral cortex and the hippocampus. Regulates voltage-gated sodium channel transport and function. May also play a role in MAPK signaling. Required for the development of axonal initial segment-targeting inhibitory GABAergic synapses made by chandelier neurons. |
| Protein Name | Fibroblast Growth Factor 13Fgf-13Fibroblast Growth Factor Homologous Factor 2Fhf-2 |
| Database Links | Reactome: R-HSA-5576892 |
| Cellular Localisation | Isoform 1: NucleusIsoform 2: CytoplasmNucleusIsoform 3: CytoplasmIsoform 4: CytoplasmIsoform 5: CytoplasmCell ProjectionFilopodiumGrowth ConeDendriteCell MembraneSarcolemmaCytoplasmNot SecretedLocalizes To The Lateral Membrane And Intercalated Disks Of Myocytes |
| Alternative Antibody Names | Anti-Fibroblast Growth Factor 13 antibodyAnti-Fgf-13 antibodyAnti-Fibroblast Growth Factor Homologous Factor 2 antibodyAnti-Fhf-2 antibodyAnti-FGF13 antibodyAnti-FHF2 antibody |
Information sourced from Uniprot.org