| Host: | Rabbit |
| Applications: | IHC/WB |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-FGF12 (180-230 aa) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Lyophilised |
| Purification: | IgG purified |
| Dilution Range: | IHC, WB (confirmed by recombinant protein). A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Storage Instruction: | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: | FGF12 |
| Gene ID: | 2257 |
| Uniprot ID: | FGF12_HUMAN |
| Immunogen Region: | 180-230 aa |
| Specificity: | Specific for FGF12. |
| Immunogen: | A synthetic peptide from aa region 180-230 of human FGF12 conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in mouse and rat. |
| Function | Involved in nervous system development and function. Involved in the positive regulation of voltage-gated sodium channel activity. Promotes neuronal excitability by elevating the voltage dependence of neuronal sodium channel SCN8A fast inactivation. |
| Protein Name | Fibroblast Growth Factor 12Fgf-12Fibroblast Growth Factor Homologous Factor 1Fhf-1Myocyte-Activating Factor |
| Database Links | Reactome: R-HSA-5576892 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Fibroblast Growth Factor 12 antibodyAnti-Fgf-12 antibodyAnti-Fibroblast Growth Factor Homologous Factor 1 antibodyAnti-Fhf-1 antibodyAnti-Myocyte-Activating Factor antibodyAnti-FGF12 antibodyAnti-FGF12B antibodyAnti-FHF1 antibody |
Information sourced from Uniprot.org
