| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-FGD4 (99-198) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
FGD4 |
| Gene ID: |
121512 |
| Uniprot ID: |
FGD4_HUMAN |
| Immunogen Region: |
99-198 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 99-198 of human FGD4 (NP_640334.2). |
| Immunogen Sequence: |
QMECEEEKAATLSSDTSIQA SEPLLDTHIVNGERDETATA PASPTTDSCDGNASDSSYRT PGIGPVLPLEERGAETETKV QERENGESPLELEQLDQHHE |
| Tissue Specificity | Expressed in different tissues, including brain, cerebellum, peripheral nerve, skeletal muscle, heart, uterus, placenta and testis. |
| Function | Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape. Activates MAPK8. |
| Protein Name | Fyve - Rhogef And Ph Domain-Containing Protein 4Actin Filament-Binding Protein FrabinFgd1-Related F-Actin-Binding ProteinZinc Finger Fyve Domain-Containing Protein 6 |
| Database Links | Reactome: R-HSA-193648Reactome: R-HSA-416482Reactome: R-HSA-9013148 |
| Cellular Localisation | CytoplasmCytoskeletonCell ProjectionFilopodiumConcentrated In Filopodia And Poorly Detected At LamellipodiaBinds Along The Sides Of Actin Fibers |
| Alternative Antibody Names | Anti-Fyve - Rhogef And Ph Domain-Containing Protein 4 antibodyAnti-Actin Filament-Binding Protein Frabin antibodyAnti-Fgd1-Related F-Actin-Binding Protein antibodyAnti-Zinc Finger Fyve Domain-Containing Protein 6 antibodyAnti-FGD4 antibodyAnti-FRABP antibodyAnti-ZFYVE6 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
