| Host: | Rabbit |
| Applications: | ELISA/IP/WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-FGD3 (250-320) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Biotin |
| Isotype: | IgG |
| Formulation: | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Purification: | Affinity Purified |
| Concentration: | 0.5-1.5 µg/µl |
| Dilution Range: | WB: 1:2, 500-1:5, 000 ELISA: 1:50, 000 IP: 1:200 IHC: 1:50-1:150 |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | FGD3 |
| Gene ID: | 89846 |
| Uniprot ID: | FGD3_HUMAN |
| Immunogen Region: | 250-320 |
| Immunogen: | Synthetic peptide taken within amino acid region 250-320 on human FYVE, RhoGEF and PH domain-containing protein 3. |
| Function | Promotes the formation of filopodia. May activate CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape. |
| Protein Name | Fyve - Rhogef And Ph Domain-Containing Protein 3 Zinc Finger Fyve Domain-Containing Protein 5 |
| Database Links | Reactome: R-HSA-193648 Reactome: R-HSA-416482 Reactome: R-HSA-9013148 |
| Cellular Localisation | Cytoplasm Cytoskeleton |
| Alternative Antibody Names | Anti-Fyve - Rhogef And Ph Domain-Containing Protein 3 antibody Anti-Zinc Finger Fyve Domain-Containing Protein 5 antibody Anti-FGD3 antibody Anti-ZFYVE5 antibody |
Information sourced from Uniprot.org