| Short Description : | Rabbit polyclonal anti-FYVE, RhoGEF and PH domain-containing protein 1 (508-558 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FGD1 |
| Gene ID: | 2245 |
| Uniprot ID: | FGD1_HUMAN |
| Immunogen: | Synthesized peptide derived from the human FGD1 at the amino acid range 508-558 |
| Immunogen Region: | 508-558 aa |
| Specificity: | This antibody detects endogenous levels of FGD1 at Human/Mouse |
| Function | Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape. |
| Protein Name | Fyve - Rhogef And Ph Domain-Containing Protein 1Faciogenital Dysplasia 1 ProteinRho/Rac Guanine Nucleotide Exchange Factor Fgd1Rho/Rac GefZinc Finger Fyve Domain-Containing Protein 3 |
| Database Links | Reactome: R-HSA-193648Reactome: R-HSA-416482Reactome: R-HSA-9013148 |
| Cellular Localisation | CytoplasmCell ProjectionLamellipodiumRuffleCytoskeletonAssociated With Membrane Ruffles And Lamellipodia |
| Alternative Antibody Names | Anti-Fyve - Rhogef And Ph Domain-Containing Protein 1 antibodyAnti-Faciogenital Dysplasia 1 Protein antibodyAnti-Rho/Rac Guanine Nucleotide Exchange Factor Fgd1 antibodyAnti-Rho/Rac Gef antibodyAnti-Zinc Finger Fyve Domain-Containing Protein 3 antibodyAnti-FGD1 antibodyAnti-FGDY antibodyAnti-ZFYVE3 antibody |
Information sourced from Uniprot.org
