Anti-Ferredoxin Reductase antibody [SRM15012] (STJ11109742)

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STJ11109742
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Host: Rabbit
Applications: WB/IF/ICC/IF-P/IHC-P/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Monoclonal
Clone ID : SRM15012
Conjugation: Unconjugated
Isotype: IgG
Purification: Affinity purification
Dilution Range: WB, 1:5000-1:30000
IF/ICC, 1:100-1:200
IF-P, 1:100-1:200
IHC-P, 1:500-1:2000
ELISA, Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: FDXR
Gene ID: 2232
Uniprot ID: ADRO_HUMAN
Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Function Serves as the first electron transfer protein in all the mitochondrial P450 systems including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver. Also acts as a ferredoxin--NADP(+) reductase essential for coenzyme Q biosynthesis: together with FDX2, transfers the electrons required for the hydroxylation reaction performed by COQ6.
Protein Name Nadph -Adrenodoxin Oxidoreductase - Mitochondrial
Ar
Adrenodoxin Reductase
Ferredoxin--Nadp(+ Reductase
Ferredoxin Reductase
Database Links Reactome: R-HSA-196108
Reactome: R-HSA-211976
Reactome: R-HSA-2395516
Reactome: R-HSA-5579026
Cellular Localisation Mitochondrion
Mitochondrion Inner Membrane
Peripheral Membrane Protein
Alternative Antibody Names Anti-Nadph -Adrenodoxin Oxidoreductase - Mitochondrial antibody
Anti-Ar antibody
Anti-Adrenodoxin Reductase antibody
Anti-Ferredoxin--Nadp(+ Reductase antibody
Anti-Ferredoxin Reductase antibody
Anti-FDXR antibody
Anti-ADXR antibody

Information sourced from Uniprot.org

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