Anti-FERMT1 antibody (STJA0007429)

SKU:
STJA0007429
£48.00 - £252.00
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Fermitin family homolog 1 is suitable for use in Western Blot research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: FERMT1
Gene ID: 55612
Uniprot ID: FERM1_HUMAN
Specificity: This antibody detects endogenous levels of Kindlin 1 at Human, Mouse
Immunogen: Synthesized peptide derived from human Kindlin 1
Function Involved in cell adhesion. Contributes to integrin activation. When coexpressed with talin, potentiates activation of ITGA2B. Required for normal keratinocyte proliferation. Required for normal polarization of basal keratinocytes in skin, and for normal cell shape. Required for normal adhesion of keratinocytes to fibronectin and laminin, and for normal keratinocyte migration to wound sites. May mediate TGF-beta 1 signaling in tumor progression.
Protein Name Fermitin Family Homolog 1
Kindlerin
Kindlin Syndrome Protein
Kindlin-1
Unc-112-Related Protein 1
Cellular Localisation Cytoplasm
Cytoskeleton
Cell Junction
Focal Adhesion
Cell Projection
Ruffle Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Constituent Of Focal Adhesions
Localized At The Basal Aspect Of Skin Keratinocytes
Close To The Cell Membrane
Colocalizes With Filamentous Actin
Upon Tgfb1 Treatment
It Localizes To Membrane Ruffles
Alternative Antibody Names Anti-Fermitin Family Homolog 1 antibody
Anti-Kindlerin antibody
Anti-Kindlin Syndrome Protein antibody
Anti-Kindlin-1 antibody
Anti-Unc-112-Related Protein 1 antibody
Anti-FERMT1 antibody
Anti-C20orf42 antibody
Anti-KIND1 antibody
Anti-URP1 antibody

Information sourced from Uniprot.org

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