| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Monoclonal |
| Clone ID: |
S5124RM |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:2000-1:20000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
FDPS |
| Gene ID: |
2224 |
| Uniprot ID: |
FPPS_HUMAN |
| Immunogen Region: |
67-419 aa |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 67-419 of human FPS/FDPS. (NP_001995.1). |
| Immunogen Sequence: |
MNGDQNSDVYAQEKQDFVQH FSQIVRVLTEDEMGHPEIGD AIARLKEVLEYNAIGGKYNR GLTVVVAFRELVEPRKQDAD SLQRAWTVGWCVELLQAFFL VADDIMDSSLTRRGQICWYQ KPGVGLDAINDANLLEACIY RLLKLYCREQPYYLNLIELF LQSSYQTEIGQTLDLLTAPQ GNVDLVRFTEKRYKSIVKYK TAFYSFYLPIAAAMYMAGID GEKEHANAKKILLEMGEFF |
| Function | Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FPP also serves as substrate for protein farnesylation and geranylgeranylation. Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate. |
| Protein Name | Farnesyl Pyrophosphate SynthaseFpp SynthaseFps(2e -6e-Farnesyl Diphosphate SynthaseDimethylallyltranstransferaseFarnesyl Diphosphate SynthaseGeranyltranstransferase |
| Database Links | Reactome: R-HSA-191273Reactome: R-HSA-2426168 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Farnesyl Pyrophosphate Synthase antibodyAnti-Fpp Synthase antibodyAnti-Fps antibodyAnti-(2e -6e-Farnesyl Diphosphate Synthase antibodyAnti-Dimethylallyltranstransferase antibodyAnti-Farnesyl Diphosphate Synthase antibodyAnti-Geranyltranstransferase antibodyAnti-FDPS antibodyAnti-FPS antibodyAnti-KIAA1293 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
