| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Fas apoptotic inhibitory molecule 3 (123-173 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
FCMR |
| Gene ID: |
9214 |
| Uniprot ID: |
FAIM3_HUMAN |
| Immunogen Region: |
123-173 aa |
| Specificity: |
This antibody detects endogenous levels of FAIM3 at Human/Mouse/Rat |
| Immunogen: |
Synthesized peptide derived from the human FAIM3 at the amino acid range 123-173 |
| Function | May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation. |
| Protein Name | Fas Apoptotic Inhibitory Molecule 3Igm Fc Fragment ReceptorRegulator Of Fas-Induced Apoptosis Toso |
| Cellular Localisation | Isoform 1: MembraneSingle-Pass Membrane ProteinIsoform 3: SecretedDetected In The Serum |
| Alternative Antibody Names | Anti-Fas Apoptotic Inhibitory Molecule 3 antibodyAnti-Igm Fc Fragment Receptor antibodyAnti-Regulator Of Fas-Induced Apoptosis Toso antibodyAnti-FCMR antibodyAnti-FAIM3 antibodyAnti-TOSO antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
