| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Low affinity immunoglobulin gamma Fc region receptor II-c (251-300 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000ELISA 1:40000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FCGR2C |
| Gene ID: | 9103 |
| Uniprot ID: | FCG2C_HUMAN |
| Immunogen Region: | 251-300 aa |
| Specificity: | CD32-C Polyclonal Antibody detects endogenous levels of CD32-C protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human FCGR2C at the amino acid range 251-300 |
| Post Translational Modifications | Phosphorylated by SRC-type Tyr-kinases such as LYN, BLK, FYN and SYK. |
| Function | Receptor for the Fc region of complexed immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. |
| Protein Name | Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-CIgg Fc Receptor Ii-CCdw32Fc-Gamma Rii-CFc-Gamma-RiicFcrii-CCd Antigen Cd32 |
| Cellular Localisation | Isoform Iic4: CytoplasmIsoform Iic3: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform Iic2: Cell MembraneIsoform Iic1: Cell Membrane |
| Alternative Antibody Names | Anti-Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-C antibodyAnti-Igg Fc Receptor Ii-C antibodyAnti-Cdw32 antibodyAnti-Fc-Gamma Rii-C antibodyAnti-Fc-Gamma-Riic antibodyAnti-Fcrii-C antibodyAnti-Cd Antigen Cd32 antibodyAnti-FCGR2C antibodyAnti-CD32 antibodyAnti-FCG2 antibodyAnti-IGFR2 antibody |
Information sourced from Uniprot.org