Host: |
Rabbit |
Applications: |
WB/ELISA |
Reactivity: |
Human/Rat/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Low affinity immunoglobulin gamma Fc region receptor II-c (251-300 aa) is suitable for use in Western Blot and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-1:2000ELISA 1:40000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
FCGR2C |
Gene ID: |
9103 |
Uniprot ID: |
FCG2C_HUMAN |
Immunogen Region: |
251-300 aa |
Specificity: |
CD32-C Polyclonal Antibody detects endogenous levels of CD32-C protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from the human FCGR2C at the amino acid range 251-300 |
Post Translational Modifications | Phosphorylated by SRC-type Tyr-kinases such as LYN, BLK, FYN and SYK. |
Function | Receptor for the Fc region of complexed immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. |
Protein Name | Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-CIgg Fc Receptor Ii-CCdw32Fc-Gamma Rii-CFc-Gamma-RiicFcrii-CCd Antigen Cd32 |
Cellular Localisation | Isoform Iic4: CytoplasmIsoform Iic3: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform Iic2: Cell MembraneIsoform Iic1: Cell Membrane |
Alternative Antibody Names | Anti-Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-C antibodyAnti-Igg Fc Receptor Ii-C antibodyAnti-Cdw32 antibodyAnti-Fc-Gamma Rii-C antibodyAnti-Fc-Gamma-Riic antibodyAnti-Fcrii-C antibodyAnti-Cd Antigen Cd32 antibodyAnti-FCGR2C antibodyAnti-CD32 antibodyAnti-FCG2 antibodyAnti-IGFR2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance