Host: |
Rabbit |
Applications: |
WB/IHC-P |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit monoclonal antibody anti-CD32 (81-95 aa) is suitable for use in Western Blot and Immunohistochemistry research applications. |
Clonality: |
Monoclonal |
Clone ID: |
R09-5D1 |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
50mM Tris-Glycine (pH7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
Purification: |
Affinity Purified |
Concentration: |
0.3 mg/ml |
Dilution Range: |
WB 1:500-1:1000IHC 1:50-1:100 |
Storage Instruction: |
Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Gene Symbol: |
FCGR2A |
Gene ID: |
2212 |
Uniprot ID: |
FCG2A_HUMAN |
Immunogen Region: |
81-95 aa |
Immunogen: |
A synthetic peptide of human CD32 |
Tissue Specificity | Found on monocytes, neutrophils and eosinophil platelets. |
Post Translational Modifications | Phosphorylated by SRC-type Tyr-kinases such as LYN, BLK, FYN, HCK and SYK. |
Function | Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens. |
Protein Name | Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-AIgg Fc Receptor Ii-ACdw32Fc-Gamma Rii-AFc-Gamma-RiiaFcrii-ACd Antigen Cd32 |
Database Links | Reactome: R-HSA-2029481Reactome: R-HSA-2029482Reactome: R-HSA-2029485Reactome: R-HSA-6798695Reactome: R-HSA-9664323 |
Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
Alternative Antibody Names | Anti-Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-A antibodyAnti-Igg Fc Receptor Ii-A antibodyAnti-Cdw32 antibodyAnti-Fc-Gamma Rii-A antibodyAnti-Fc-Gamma-Riia antibodyAnti-Fcrii-A antibodyAnti-Cd Antigen Cd32 antibodyAnti-FCGR2A antibodyAnti-CD32 antibodyAnti-FCG2 antibodyAnti-FCGR2A1 antibodyAnti-IGFR2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance