Anti-FCF1 antibody (100-198) (STJ119324)

Name: Anti-FCF1 antibody (100-198) (STJ119324)
SKU: STJ119324
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ119324

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Short Description	Rabbit polyclonal FCF1 (100-198) antibody for use in WB, IHC-P, IF, ICC and ELISA in human and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/IHC-P/IF/ICC/ELISA
Host	Rabbit
Reactivity	Human/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:2000 IHC-P:1:50-1:200 IF/ICC:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	FCF1
Gene ID	51077
Uniprot ID	FCF1_HUMAN
Immunogen Region	100-198
Immunogen Sequence	PCITDCVMAEIEKLGQKYRV ALRIAKDPRFERLPCTHKGT YADDCLVQRVTQHKCYIVAT VDRDLKRRIRKIPGVPIMYI SNHRYNIERMPDDYGAPRF
Specificity	A synthetic peptide corresponding to a sequence within amino acids 100-198 of human FCF1 (NP_057046.1).

Function	Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
Protein Name	Rrna-Processing Protein Fcf1 Homolog
Database Links	Reactome: R-HSA-6790901 Reactome: R-HSA-6791226
Cellular Localisation	Nucleus Nucleolus
Alternative Antibody Names	Anti-Rrna-Processing Protein Fcf1 Homolog antibody Anti-FCF1 antibody Anti-C14orf111 antibody Anti-CGI-35 antibody

Information sourced from Uniprot.org