| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FCF1 |
| Gene ID: | 51077 |
| Uniprot ID: | FCF1_HUMAN |
| Immunogen Region: | 100-198 |
| Immunogen Sequence: | PCITDCVMAEIEKLGQKYRV ALRIAKDPRFERLPCTHKGT YADDCLVQRVTQHKCYIVAT VDRDLKRRIRKIPGVPIMYI SNHRYNIERMPDDYGAPRF |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 100-198 of human FCF1 (NP_057046.1). |
| Function | Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. |
| Protein Name | Rrna-Processing Protein Fcf1 Homolog |
| Database Links | Reactome: R-HSA-6790901Reactome: R-HSA-6791226 |
| Cellular Localisation | NucleusNucleolus |
| Alternative Antibody Names | Anti-Rrna-Processing Protein Fcf1 Homolog antibodyAnti-FCF1 antibodyAnti-C14orf111 antibodyAnti-CGI-35 antibody |
Information sourced from Uniprot.org
