• Human appendix tissue was stained with anti-CD23 (ABT-CD23) antibody.
  • Human diffuse large B-cell lymphoma tissue was stained with Anti-CD23 (ABT-CD23) Antibody
  • Human tonsil tissue was stained with anti-CD23 (ABT-CD23) antibody.

Anti-FCER2 antibody (200-321 aa) [ABT-CD23] (STJ196746)

SKU:
STJ196746

Current Stock:
Host: Mouse
Applications: IHC/IF
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Low affinity immunoglobulin epsilon Fc receptor (200-321 aa) is suitable for use in Immunohistochemistry and Immunofluorescence research applications.
Clonality: Monoclonal
Clone ID: ABT-CD23
Conjugation: Unconjugated
Isotype: IgG1k
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Dilution Range: IHC-P 1:100-500
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: FCER2
Gene ID: 2208
Uniprot ID: FCER2_HUMAN
Immunogen Region: 200-321 aa
Specificity: This antibody detects endogenous levels of human CD23. Heat-induced epitope retrieval (HIER) Citrate buffer of pH6.0 was highly recommended as antigen repair method in paraffin section
Immunogen: Synthesized peptide derived from the human CD23 at the amino acid range 200-321
Function Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B cells. On B cells, initiates IgE-dependent antigen uptake and presentation to T cells. On macrophages, upon IgE binding and antigen cross-linking induces intracellular killing of parasites through activation of L-Arginine-nitric oxide pathway.
Protein Name Low Affinity Immunoglobulin Epsilon Fc Receptor
Blast-2
C-Type Lectin Domain Family 4 Member J
Fc-Epsilon-Rii
Immunoglobulin E-Binding Factor
Lymphocyte Ige Receptor
Cd Antigen Cd23 Cleaved Into - Low Affinity Immunoglobulin Epsilon Fc Receptor Membrane-Bound Form - Low Affinity Immunoglobulin Epsilon Fc Receptor Soluble Form
Database Links Reactome: R-HSA-2197563
Reactome: R-HSA-6783783
Reactome: R-HSA-6785807
Cellular Localisation Cell Membrane
Single-Pass Type Ii Membrane Protein
Lipid-Anchor
Secreted
Also Exists As A Soluble Excreted Form
Scd23
Alternative Antibody Names Anti-Low Affinity Immunoglobulin Epsilon Fc Receptor antibody
Anti-Blast-2 antibody
Anti-C-Type Lectin Domain Family 4 Member J antibody
Anti-Fc-Epsilon-Rii antibody
Anti-Immunoglobulin E-Binding Factor antibody
Anti-Lymphocyte Ige Receptor antibody
Anti-Cd Antigen Cd23 Cleaved Into - Low Affinity Immunoglobulin Epsilon Fc Receptor Membrane-Bound Form - Low Affinity Immunoglobulin Epsilon Fc Receptor Soluble Form antibody
Anti-FCER2 antibody
Anti-CD23A antibody
Anti-CLEC4J antibody
Anti-FCE2 antibody
Anti-IGEBF antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance