• Western blot analysis of extracts of 293T cells, using FCAR antibody (STJ111464). Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% non-fat dry milk in TBST.
  • Western blot analysis of lysates from 293T cells, using FCAR Rabbit polyclonal antibody (STJ111464). Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST.

Anti-FCAR antibody (60-287) (STJ111464)

SKU:
STJ111464

£112.50 - £522.50
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Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-FCAR (60-287) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:200-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: FCAR
Gene ID: 2204
Uniprot ID: FCAR_HUMAN
Immunogen Region: 60-287
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 60-287 of human FCAR (NP_001991.1).
Immunogen Sequence: LMIIKNSTYREIGRRLKFWN ETDPEFVIDHMDANKAGRYQ CQYRIGHYRFRYSDTLELVV TGLYGKPFLSADRGLVLMPG ENISLTCSSAHIPFDRFSLA KEGELSLPQHQSGEHPANFS LGPVDLNVSGIYRCYGWYNR SPYLWSFPSNALELVVTDSI HQDYTTQNLIRMAVAGLVLV ALLAILVENWHSHTALNKEA SADVAEPSWSQQMCQPGLTF ARTPSVCK
Tissue Specificity Isoform A.1, isoform A.2 and isoform A.3 are differentially expressed between blood and mucosal myeloid cells. Isoform A.1, isoform A.2 and isoform A.3 are expressed in monocytes. Isoform A.1 and isoform A.2 are expressed in alveolar macrophages.however only one isoform is expressed at alveolar macrophages surfaces.
Function Binds to the Fc region of immunoglobulins alpha. Mediates several functions including cytokine production.
Protein Name Immunoglobulin Alpha Fc Receptor
Iga Fc Receptor
Cd Antigen Cd89
Database Links Reactome: R-HSA-6798695
Cellular Localisation Isoform A
1: Cell Membrane
Single-Pass Type I Membrane Protein
2: Cell Membrane
3: Cell Membrane
Isoform B: Secreted
Isoform B-Delta-S2: Secreted
Alternative Antibody Names Anti-Immunoglobulin Alpha Fc Receptor antibody
Anti-Iga Fc Receptor antibody
Anti-Cd Antigen Cd89 antibody
Anti-FCAR antibody
Anti-CD89 antibody

Information sourced from Uniprot.org

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