Anti-FBXO32 antibody (240-280) {Biotin} (STJ500184)

SKU:
STJ500184-100

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Host: Rabbit
Applications: ELISA/IHC/IP/WB
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-FBXO32 (240-280) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Biotin
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.64-0.72 µg/µl
Dilution Range: WB: 1:500
DB: 1:10, 000
ELISA: 1:10, 000
IP: 1:200
IHC: 1:50-1:150
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: FBXO32
Gene ID: 114907
Uniprot ID: FBX32_HUMAN
Immunogen Region: 240-280
Immunogen: Synthetic peptide taken within amino acid region 240-280 on Atr1 protein.
Tissue Specificity Specifically expressed in cardiac and skeletal muscle.
Function Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins during skeletal muscle atrophy. Recognizes TERF1.
Protein Name F-Box Only Protein 32
Atrogin-1
Muscle Atrophy F-Box Protein
Mafbx
Database Links Reactome: R-HSA-8951664
Reactome: R-HSA-9615017
Reactome: R-HSA-983168
Cellular Localisation Cytoplasm
Nucleus
Shuttles Between Cytoplasm And The Nucleus
Alternative Antibody Names Anti-F-Box Only Protein 32 antibody
Anti-Atrogin-1 antibody
Anti-Muscle Atrophy F-Box Protein antibody
Anti-Mafbx antibody
Anti-FBXO32 antibody

Information sourced from Uniprot.org

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