Anti-FBP2 antibody (1-339aa) [AT1E11] (STJA0041635)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1k
ImmunogenRecombinant human FBP2 (1-339aa) purified from E. coli
General Information
| Short Description | Mouse monoclonal anti-FBP2 (1-339aa) for use in ELISA and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/WB |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | AT1E11 |
| Isotype | IgG1k |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | By protein-G affinity chromatography |
| Formulation | Liquid in phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | FBP2 |
| Gene ID | 8789 |
| Uniprot ID | F16P2_HUMAN |
| Accession Number | NP_003828 |
| Immunogen | Recombinant human FBP2 (1-339aa) purified from E. coli |
| Immunogen Region | 1-339aa |
Additional Info
| Tissue Specificity | Expressed in skeletal muscle (at protein level). |
| Function | Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations and probably participates in glycogen synthesis from carbohydrate precursors, such as lactate. |
| Protein Name | Fructose-1 -6-Bisphosphatase Isozyme 2Fbpase 2D-Fructose-1 -6-Bisphosphate 1-Phosphohydrolase 2Muscle Fbpase |
| Database Links | Reactome: R-HSA-70263 |
| Cellular Localisation | Cell JunctionCytoplasmNucleusMyofibrilSarcomereZ LineIn Neonatal CardiomyocytesDistributed Throughout The CytosolAccumulating In The Intercalated Disks Which Occur At The Z Line Of Cardiomyocytes And Connect Adjacent CellsAnd Also Located In The NucleusDissociates From The Z Line Following An Increase In Cytosolic Ca(2+) ConcentrationIn Muscle Precursor CellsLocalizes Predominantly To The Nucleus And To A Lesser Extent To The Cytoplasm At The Proliferative PhaseWhile Mainly Localizing To The Cytoplasm At The Differentiation PhaseColocalizes With Aldoa And Alpha-Actinin On Both Sides Of The Z Line Of Skeletal MuscleDissociates Rapidly From The Z Line Following An Increase In Cytosolic Ca(2+) Concentration |
| Alternative Antibody Names | Anti-Fructose-1 -6-Bisphosphatase Isozyme 2 antibodyAnti-Fbpase 2 antibodyAnti-D-Fructose-1 -6-Bisphosphate 1-Phosphohydrolase 2 antibodyAnti-Muscle Fbpase antibodyAnti-FBP2 antibody |
Information sourced from Uniprot.org