Anti-FAU antibody (1-133) (STJ114074)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal FAU (1-133) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | FAU |
| Gene ID | 2197 |
| Uniprot ID | RS30_HUMAN |
| Immunogen Region | 1-133 |
| Immunogen Sequence | MQLFVRAQELHTFEVTGQET VAQIKAHVASLEGIAPEDQV VLLAGAPLEDEATLGQCGVE ALTTLEVAGRMLGGKVHGSL ARAGKVRGQTPKVAKQEKKK KKTGRAKRRMQYNRRFVNVV PTFGKKKGPNANS |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-133 of human FAU (NP_001988.1). |
Additional Info
| Post Translational Modifications | FUBI is cleaved from ribosomal protein S30 by the deubiquitinase USP36 before the assembly of ribosomal protein S30 into pre-40S ribosomal particles. FUBI removal from ribosomal protein S30 is a crucial event for the final maturation of pre-40S particles. |
| Function | Ubiquitin-like protein FUBI: May have pro-apoptotic activity. Small ribosomal subunit protein eS30: Component of the 40S subunit of the ribosome. Contributes to the assembly and function of 40S ribosomal subunits. |
| Protein Name | Ubiquitin-Like Fubi-Ribosomal Protein Es30 Fusion ProteinFau Ubiquitin Like And Ribosomal Protein S30 Fusion Cleaved Into - Ubiquitin-Like Protein Fubi - Small Ribosomal Subunit Protein Es3040s Ribosomal Protein S30 |
| Database Links | Reactome: R-HSA-156827Reactome: R-HSA-156902Reactome: R-HSA-1799339Reactome: R-HSA-192823Reactome: R-HSA-2408557Reactome: R-HSA-6791226Reactome: R-HSA-72649Reactome: R-HSA-72689Reactome: R-HSA-72695Reactome: R-HSA-72702Reactome: R-HSA-72706Reactome: R-HSA-72764Reactome: R-HSA-9010553Reactome: R-HSA-9633012Reactome: R-HSA-9735869Reactome: R-HSA-9754678Reactome: R-HSA-975956Reactome: R-HSA-975957 |
| Cellular Localisation | Small Ribosomal Subunit Protein Es30: CytoplasmNucleus |
| Alternative Antibody Names | Anti-Ubiquitin-Like Fubi-Ribosomal Protein Es30 Fusion Protein antibodyAnti-Fau Ubiquitin Like And Ribosomal Protein S30 Fusion Cleaved Into - Ubiquitin-Like Protein Fubi - Small Ribosomal Subunit Protein Es30 antibodyAnti-40s Ribosomal Protein S30 antibodyAnti-FAU antibody |
Information sourced from Uniprot.org