| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FAU |
| Gene ID: | 2197 |
| Uniprot ID: | RS30_HUMAN |
| Immunogen Region: | 1-133 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-133 of human FAU (NP_001988.1). |
| Immunogen Sequence: | MQLFVRAQELHTFEVTGQET VAQIKAHVASLEGIAPEDQV VLLAGAPLEDEATLGQCGVE ALTTLEVAGRMLGGKVHGSL ARAGKVRGQTPKVAKQEKKK KKTGRAKRRMQYNRRFVNVV PTFGKKKGPNANS |
| Post Translational Modifications | FUBI is cleaved from ribosomal protein S30 by the deubiquitinase USP36 before the assembly of ribosomal protein S30 into pre-40S ribosomal particles. FUBI removal from ribosomal protein S30 is a crucial event for the final maturation of pre-40S particles. |
| Function | Ubiquitin-like protein FUBI: May have pro-apoptotic activity. Small ribosomal subunit protein eS30: Component of the 40S subunit of the ribosome. Contributes to the assembly and function of 40S ribosomal subunits. |
| Protein Name | Ubiquitin-Like Fubi-Ribosomal Protein Es30 Fusion ProteinFau Ubiquitin Like And Ribosomal Protein S30 Fusion Cleaved Into - Ubiquitin-Like Protein Fubi - Small Ribosomal Subunit Protein Es3040s Ribosomal Protein S30 |
| Database Links | Reactome: R-HSA-156827Reactome: R-HSA-156902Reactome: R-HSA-1799339Reactome: R-HSA-192823Reactome: R-HSA-2408557Reactome: R-HSA-6791226Reactome: R-HSA-72649Reactome: R-HSA-72689Reactome: R-HSA-72695Reactome: R-HSA-72702Reactome: R-HSA-72706Reactome: R-HSA-72764Reactome: R-HSA-9010553Reactome: R-HSA-9633012Reactome: R-HSA-9735869Reactome: R-HSA-9754678Reactome: R-HSA-975956Reactome: R-HSA-975957 |
| Cellular Localisation | Small Ribosomal Subunit Protein Es30: CytoplasmNucleus |
| Alternative Antibody Names | Anti-Ubiquitin-Like Fubi-Ribosomal Protein Es30 Fusion Protein antibodyAnti-Fau Ubiquitin Like And Ribosomal Protein S30 Fusion Cleaved Into - Ubiquitin-Like Protein Fubi - Small Ribosomal Subunit Protein Es30 antibodyAnti-40s Ribosomal Protein S30 antibodyAnti-FAU antibody |
Information sourced from Uniprot.org
![Immunofluorescence analysis of U-2 OS cells using [KO Validated] IFITM3 Rabbit polyclonal antibody (STJ115037) at dilution of 1:100. Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/94077/375456/STJ115037_1__41009.1713142223.jpg?c=1 "Immunofluorescence analysis of U-2 OS cells using [KO Validated] IFITM3 Rabbit polyclonal antibody (STJ115037) at dilution of 1:100. Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.")
