Function | Involved in the regulation of endoplasmic reticulum (ER)-mitochondria coupling. Negatively regulates the ER-mitochondria distance and Ca(2+) transfer from ER to mitochondria possibly implicating it in the regulation of apoptosis. May collaborate with RNF183 to restrain BIK protein levels thus regulating apoptotic signaling. |
Protein Name | Fetal And Adult Testis-Expressed Transcript ProteinCancer/Testis Antigen 43Ct43Tumor Antigen Bj-Hcc-2 |
Cellular Localisation | MitochondrionMitochondrion Outer MembraneEndoplasmic Reticulum MembraneSingle-Pass Membrane ProteinCytoplasmic SideLocalized To Specific Membrane Structures Termed Mitochondria-Associated Membranes (Mams) Which Connect The Endoplasmic Reticulum (Er) And The MitochondriaAlso Associated With The Outer Surface Of Mitochondria At Sites That Are Not In Close Contact With The Er |
Alternative Antibody Names | Anti-Fetal And Adult Testis-Expressed Transcript Protein antibodyAnti-Cancer/Testis Antigen 43 antibodyAnti-Ct43 antibodyAnti-Tumor Antigen Bj-Hcc-2 antibodyAnti-FATE1 antibodyAnti-FATE antibody |
Information sourced from Uniprot.org