Anti-FATE1 antibody (STJA0008976)

SKU:
STJA0008976

Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Fetal and adult testis-expressed transcript protein is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: FATE1
Gene ID: 89885
Uniprot ID: FATE1_HUMAN
Specificity: This antibody detects endogenous levels of FATE1 at Human
Immunogen: Synthesized peptide derived from human FATE1
Function Involved in the regulation of endoplasmic reticulum (ER)-mitochondria coupling. Negatively regulates the ER-mitochondria distance and Ca(2+) transfer from ER to mitochondria possibly implicating it in the regulation of apoptosis. May collaborate with RNF183 to restrain BIK protein levels thus regulating apoptotic signaling.
Protein Name Fetal And Adult Testis-Expressed Transcript Protein
Cancer/Testis Antigen 43
Ct43
Tumor Antigen Bj-Hcc-2
Cellular Localisation Mitochondrion
Mitochondrion Outer Membrane
Endoplasmic Reticulum Membrane
Single-Pass Membrane Protein
Cytoplasmic Side
Localized To Specific Membrane Structures Termed Mitochondria-Associated Membranes (Mams) Which Connect The Endoplasmic Reticulum (Er) And The Mitochondria
Also Associated With The Outer Surface Of Mitochondria At Sites That Are Not In Close Contact With The Er
Alternative Antibody Names Anti-Fetal And Adult Testis-Expressed Transcript Protein antibody
Anti-Cancer/Testis Antigen 43 antibody
Anti-Ct43 antibody
Anti-Tumor Antigen Bj-Hcc-2 antibody
Anti-FATE1 antibody
Anti-FATE antibody

Information sourced from Uniprot.org

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