| Host: | Rabbit |
| Applications: | IHC/IF |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Protocadherin Fat 1 (1140-1220 aa) is suitable for use in Immunohistochemistry and Immunofluorescence research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | IHC-P 1:50-300IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FAT1 |
| Gene ID: | 2195 |
| Uniprot ID: | FAT1_HUMAN |
| Immunogen Region: | 1140-1220 aa |
| Specificity: | FAT1 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 1140-1220 |
| Post Translational Modifications | Undergoes proteolytic cleavage. The extracellular domain is cleaved off and the cytoplasmic domain (about 400 AA) shuttles to the nucleus. |
| Function | Protocadherin Fat 1: Plays an essential role for cellular polarization, directed cell migration and modulating cell-cell contact. |
| Protein Name | Protocadherin Fat 1Cadherin Family Member 7Cadherin-Related Tumor Suppressor HomologProtein Fat Homolog Cleaved Into - Protocadherin Fat 1 - Nuclear Form |
| Cellular Localisation | Protocadherin Fat 1: Cell MembraneSingle-Pass Type I Membrane ProteinProtocadherin Fat 1Nuclear Form: Nucleus |
| Alternative Antibody Names | Anti-Protocadherin Fat 1 antibodyAnti-Cadherin Family Member 7 antibodyAnti-Cadherin-Related Tumor Suppressor Homolog antibodyAnti-Protein Fat Homolog Cleaved Into - Protocadherin Fat 1 - Nuclear Form antibodyAnti-FAT1 antibodyAnti-CDHF7 antibodyAnti-FAT antibody |
Information sourced from Uniprot.org