| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-FAST kinase domain-containing protein 2, mitochondrial (171-220 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000ELISA 1:5000IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FASTKD2 |
| Gene ID: | 22868 |
| Uniprot ID: | FAKD2_HUMAN |
| Immunogen Region: | 171-220 aa |
| Specificity: | FASTKD2 Polyclonal Antibody detects endogenous levels of FASTKD2 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human FAKD2 at the amino acid range 171-220 |
| Function | Plays an important role in assembly of the mitochondrial large ribosomal subunit. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation. May play a role in mitochondrial apoptosis. |
| Protein Name | Fast Kinase Domain-Containing Protein 2 - Mitochondrial |
| Database Links | Reactome: R-HSA-9837092 |
| Cellular Localisation | Mitochondrion MatrixMitochondrion NucleoidLocalizes To Mitochondrial Rna Granules Found In Close Proximity To The Mitochondrial Nucleoids |
| Alternative Antibody Names | Anti-Fast Kinase Domain-Containing Protein 2 - Mitochondrial antibodyAnti-FASTKD2 antibodyAnti-KIAA0971 antibody |
Information sourced from Uniprot.org